Good morning, Missoula.

Pharmaceutical company Tonix Pharmaceuticals broke ground on Oct.

8 in Hamilton in the Bitterroot Valley; the new facility will develop monoclonal antibody medicines for Lyme disease and create 25 to 200 jobs, with products expected in four to five years. CEO Seth Lederman said the project supports local biotech growth.

Small business owners in Montana are cautious this fall with worker shortages and rising costs, according to a recent NFIB survey.

NFIB Montana Director Ronda Wiggers said the state should keep its pro-small-business policies — a key step as uncertainty continues.

Thousands of fish were saved from irrigation ditches, and Montana Trout Unlimited is seeking funds to install a fish screen (which would keep them out) to protect local water quality.

The Centers for Medicare and Medicaid Services will start sending $500 refund checks to over 14,000 eligible Montanans this month, returning more than $7 million in ACA overcharges.

Montana Grizzlies will host the Idaho Vandals for a second season, with Idaho QB Joshua Wood saying they want to change last year’s result — hinting at unfinished business ahead.